Objective The interleukin (IL)23 pathway contributes to IBD pathogenesis and is being actively studied as a therapeutic target in patients with IBD. Unexpected outcomes in these therapeutic trials ...
1 National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands 2 Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands ...
Background Gut microbiota dysbiosis is linked to autism spectrum disorder (ASD) in children. However, the role of bacterial ...
3 Colorectal Cancer Genetics and Polyposis Registry, Cancer Research UK Colorectal Cancer Unit, St Mark’s Hospital, Harrow, Middlesex, UK, and Molecular and Population Genetics, Cancer Research UK, 44 ...
Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035
Objectives The incidence of gastric cancer continues to decrease globally, approaching levels that in some populations could define it as a rare disease. To explore this on a wider scale, we predict ...
Objective The aim of this study was to assess the efficacy and safety of adalimumab (ADA), a recombinant human monoclonal antibody against tumour necrosis factor α (TNF), for the induction of clinical ...
Objective Proton pump inhibitors (PPIs) are drugs used to suppress gastric acid production and treat GI disorders such as peptic ulcers and gastro-oesophageal reflux. They have been considered low ...
4 Division of Gastroenterology and Hepatology, Department of Internal Medicine, Baylor College of Medicine, Houston, Texas, USA Correspondence to Dr Siddharth Singh, Division of Gastroenterology and ...
1 Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia 2 Department of Psychology, Macquarie University, North Ryde, New South Wales, Australia 3 Department of ...
1 Department of General Practice and Health Services Research, University Medical Hospital, Heidelberg, Germany 2 Department of Psychosomatic Medicine, University Medical Hospital Tübingen, Germany 3 ...
Correspondence to Dr Tonya Kaltenbach, Veterans Affairs Palo Alto, Stanford University School of Medicine, Palo Alto, CA 94304, USA; endoresection{at}me.com or tonya.kaltenbach{at}va.gov Background ...
The aim of this study was to establish the relative importance of risk factors for mortality after acute upper gastrointestinal haemorrhage, and to formulate a simple numerical scoring system that ...
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