Proliferating cells, in particular tumor cells, express a dimeric isoenzyme of pyruvate kinase, termed Tumor M2 pyruvate kinase. In the last few years, much attention has been paid to this novel ...

Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes ...

In combination with established tumor markers, EDTA-plasma Tumor M2-PK ... PK testing is a good noninvasive screening parameter for colorectal cancer with a reported sensitivity of 68.8-91.0% ...