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Foralumab is the first fully human anti-CD3 monoclonal antibody administered via the intranasal route. This novel, non-systemic approach is designed to engage regulatory T cells, promoting immune ...
AP402 targets p95HER2, a truncated form of HER2 present in 30-40% of HER2-positive cancers, which is associated with exceptionally poor prognosis, and not addressable by conventional anti-HER2 ...
BASEL, Switzerland I April 14, 2025 I Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the European Commission has approved Columvi® (glofitamab) in ...
State Key Laboratory of Medical Proteomics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China University of Chinese Academy of Sciences, Beijing 101408, China ...
Attribution (BY): Credit must be given to the creator. Immunoreagents, most commonly antibodies, are integral components of lateral flow immunoassays. However, the use of antibodies comes with ...
Antibodies are one of the most specific tools for the detection and capture of molecular targets. The right antibody can play a key role in revealing the presence, quantity, dynamics, and even ...
IHC protocols in basic research laboratories are generally performed manually with the goal of labeling multiple antigens simultaneously. The current standard for this is using fluorescently labeled ...
Data analysis was done using STARe Default DB V.16. The Far-UV CD spectroscopy was performed to analyze secondary structure of antibodies using a Jasco J-815 spectropolarimeter (Jasco). The UV CD ...
The LgBiT and SmBiT subunits are linked to a pair of secondary antibodies from two distinct species in the Lumit TM Immunoassay Cellular System. Seeded cells are lysed in a multiwell plate using a ...
Protein samples were separated onto 7–9% acrylamide/bisacrylamide gel, transferred to a nitrocellulose membrane and probed with the appropriate primary and HRP-conjugated secondary antibodies.
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