For decades, scientists viewed the genome of a newly fertilized egg as a structural "blank slate"—a disordered tangle of DNA ...

For decades, scientists believed a fertilized egg’s DNA began as a shapeless mass, only organizing itself once the embryo switched on its genes. But new research reveals that the genome is already ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.