A significant advancement in molecular engineering has produced a large, hollow spherical shell nanostructure through the self-assembly of peptides and metal ions, report researchers from Japan. This ...

Cells have a trick called splicing. They can cut a gene's message into pieces and decide which fragments to keep. By mixing ...

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read ...

How do memories last a lifetime when the molecules that form them turn over within days, weeks or months? An interaction ...

A research team has uncovered a previously unknown type of immune signaling molecule—a novel compound combining histidine and ...

Background IBD is a chronic inflammatory condition driven by complex genetic and immune interactions, yet preclinical models ...

Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, U.K.

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

For instance, though generative AI has been very successful in determining protein structure, similar programs frequently suggest small molecule structures that cannot actually be synthesized ...

Reviewing the molecule structure is essential to determine the drug type. Some drugs may be available as either non-salt (covalent) molecules or as salts (e.g., phenobarbital and sodium phenobarbital; ...