National Key-Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and ...

First synthetic 'mini prion' shows how protein misfolding multiplies Model enables study of fundamental interactions underlying neurodegenerative disease Date: April 28, 2025 Source: Northwestern ...

Jeffrey Parkin (he/him) has been writing video game guides for Polygon for almost seven years. He has learned to love just about every genre of game that exists. There are a lot of diseases in The ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The “mini prion” folds and stacks ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The "mini prion" folds and stacks ...

This "mini prion" induces misfolding in normal tau, and its behavior is influenced by water structure around the protein, particularly by the P301L mutation. These findings may aid in developing ...

Prion diseases were first observed in humans in the form of kuru, a degenerative disease found among people in Papua New Guinea. It's possible that the disease started as a heritable genetic trait, ...