If, as expected, they prove safer and provide longer lasting therapeutic gene expression, adenovirus vectors like the one that killed Jesse Gelsinger will likely be phased out for most diseases. Why ...

David Mack/Photo Researchers, Inc. Since 1998, when 18-year-old Jesse Gelsinger died in a clinical trial at the University of Pennsylvania, the news on gene therapy hasn't gotten much better. In a ...

He became widely known as the lead scientist in a gene therapy trial that led to the 1999 death of 18-year-old Jesse Gelsinger, the first person to die as a result of gene therapy. The tragedy led ...

met on 8–10 December to examine the clinical trial in which Jesse Gelsinger became the first person to die from the experimental technique of gene therapy. The RAC responded to his death by ...