perform an assay that measures Factor VIII inhibitor concentration. Monitor plasma FVIII activity using a chromogenic assay or one-stage clotting assay. If one-stage clotting assay is used ...

for bleeding prophylaxis in patients aged 12 years or older with hemophilia A and B with or without factor VIII or IX inhibitors. Fitusiran is a first-in-class small interfering RNA therapeutic ...

with or without factor VIII or IX inhibitors (neutralizing antibodies). "Today's approval of Qfitlia is significant for patients with hemophilia because it can be administered less frequently than ...