RNA-based technologies are a powerful molecular biology toolbox, empowering scientists to decipher the complexities of living ...

The RNA cloud formed around genes regulates their readout into RNA. Triplexes help define where in the genome a cloud forms. Proteins and other fl ...

With this level of control, scientists can fine-tune how nanomedicines interact with the human body. These new designs are ...

A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The specific location of each atom ...

Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.

Alkanediols such as 1,6-hexanediol disrupt many phase-separated condensates in cellula and in vitro, but how molecular interactions are perturbed by these compounds remains unclear. This study uses ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

SNAs are a globular form of DNA that can easily enter cells and bind to targets. More effective than linear DNA of the same sequence, SNAs have demonstrated significant potential in gene regulation, ...

UT researchers have created an alternative to Edman degradation for protein sequencing using bases instead of acid ...

Tda1 protein kinase, activated by Snf1 and yeast GSK3-β, fine-tunes metabolism through the phosphorylation of Hxk2, which is implicated in yeast glucose repression. Tda1 is activated by both Snf1 and ...