The EMBO Journal

Predictability of the community‐function landscape in wine yeast ecosystems

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Predictively linking taxonomic composition and ...
The EMBO Journal

Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Piccolino regulates ribbon morphology as well ...
The EMBO Journal

Graft conditioning with fluticasone propionate reduces graft‐versus‐host disease upon allogeneic hematopoietic cell transplantation in mice

Hematopoietic cell transplantation (HCT) treats many blood conditions but remains underused due to complications such as graft‐versus‐host disease (GvHD). In GvHD, donor immune cells attack the ...
The EMBO Journal

New plastids, old proteins: repeated endosymbiotic acquisitions in kareniacean dinoflagellates

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Kareniacean plastids are distinct from those ...
The EMBO Journal

Genome‐wide association and environmental suppression of the mortal germline phenotype of wild C. elegans

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Many C. elegans wild strains become sterile ...
The EMBO Journal

RZZ‐Spindly and CENP‐E form an integrated platform to recruit dynein to the kinetochore corona

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chromosome biorientation on the mitotic ...
The EMBO Journal

Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Evolutionary repair in sef1Δ mutant cells of ...
The EMBO Journal

DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression

Cortical neurogenesis depends on the balance between self‐renewal and differentiation of apical progenitors (APs). Here, we study the epigenetic control of AP's division mode by focusing on the ...
The EMBO Journal

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

imageimageGenome-wide p53 protein stability screens provide a comprehensive network view of the processes regulating wild type and mutant p53 and uncover potential targets for reinforcing wild-type ...
The EMBO Journal

mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Fragile X syndrome (FXS) is the leading cause ...
The EMBO Journal

Wengen’s hidden powers: ROS triggers a TNFR-dependent tissue regenerative pathway in Drosophila

While the role of the Tumor necrosis factor-α (referred to as TNF here) as a key mediator of pro-inflammatory and immune responses is well-established, non-pathological functions of the TNF-TNF ...
The EMBO Journal

APP substrate ectodomain defines amyloid‐β peptide length by restraining γ‐secretase processivity and facilitating product release

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Sequential proteolysis of amyloid precursor ...