Background Gut microbiota dysbiosis is linked to autism spectrum disorder (ASD) in children. However, the role of bacterial ...
Objective The interleukin (IL)23 pathway contributes to IBD pathogenesis and is being actively studied as a therapeutic target in patients with IBD. Unexpected outcomes in these therapeutic trials ...
Objectives Many cross-sectional surveys have reported the prevalence of uninvestigated dyspepsia, but there has been no recent systematic review of data from all studies to determine its global ...
With great interest, we read the review article by Agus et al , which suggested that gut microbiome alterations could affect metabolic homeostasis.1 Moreover, gut microbiome alterations in concert ...
Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035
Objectives The incidence of gastric cancer continues to decrease globally, approaching levels that in some populations could define it as a rare disease. To explore this on a wider scale, we predict ...
Objective Bile acids are regulators of lipid and glucose metabolism, and modulate inflammation in the liver and other tissues. Primary bile acids such as cholic acid and chenodeoxycholic acid (CDCA) ...
The aim of this study was to establish the relative importance of risk factors for mortality after acute upper gastrointestinal haemorrhage, and to formulate a simple numerical scoring system that ...
Section of Cancer Genetics, Institute of Cancer Research, Sutton, UK Dr A Walther, Molecular and Population Genetics, London Research Institute, Cancer Research UK, 44 Lincoln’s Inn Fields, London ...
Objectives In patients with IBD experiencing an immune-mediated loss of response (LOR) to antitumour necrosis factor (anti-TNF), algorithms recommend a switch of anti-TNF without immunosuppressive ...
Dr G Fattovich, Servizio Autonomo Clinicizzato di Gastroenterologia, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Università di Verona, Via delle Menegone 10, 37134 Verona, Italy ...
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Objective To monitor trastuzumab resistance and determine the underlying mechanisms for the limited response rate and rapid emergence of resistance of HER2+ metastatic gastric cancer (mGC). Design ...
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