Immunologists from the Institute have been the first to uncover a role for a family of RNA binding proteins in the function ...

The body has an intricate system to defend against infections where each type of immune cell plays a distinct role. Now, a ...

Indiana University School of Medicine scientists have developed a new method that shifts the behavior of immunosuppressive ...

Scientists have uncovered a sweet twist in the body’s fight against cancer. Glucose, best known as the fuel that powers our ...

Special T cells known as ‘CD8+ T cells’ are responsible for directly identifying and targeting infected cells. In the context of cancer, these cells lose their function and allow tumors to progress.

Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 T cells, teaching them how to mount lasting defenses after vaccination.

A “complete eradication” of B cells with chimeric antigen receptor T-cell therapy is responsible for the long-term, drug-free remission from autoimmune diseases observed after treatment, according to ...

Findings indicate that frequent COVID-19 booster shots do not weaken T-cell responses, alleviating concerns for vulnerable groups facing new variants.

Sickle cell disease changes CD8+ T-cell chromatin structure, affecting cancer immunotherapy response.

Transcription factor T-bet regulates memory B cell subsetsT-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma ...