RNA vaccines are a new class of vaccines that are composed of an mRNA sequence coding for a pathogen-specific protein (antigen). Once expressed in the body, the target antigen is recognized by the ...

In a previous study, Jayaram successfully differentiated between coding and non-coding parts of genes based on chemical properties of the DNA sequence (PLoS One, DOI: 10.1371/journal.pone.0012433).

A DNA sequence code critical to our understanding of how human genes are turned on and off has just been unlocked by a team of scientists. Molecular biologists refer to this code as the “human ...

Differential arginylation of actin isoforms is regulated at the level of their nucleotide coding sequence. This regulation is a dynamic event that dynamically responds to cellular stimuli and is ...

Superimposed on the genetic sequences coding for amino acids is a second genetic code. This second genetic code, which makes use of dual-use codons, or duons, specifies how genes are controlled ...

Discovering the Functions of Noncoding Sequence Variants Neville Sanjana explored noncoding genomic regions by combining pooled CRISPR screening and single cell sequencing.

Daniel E. Eyler, Monika K. Franco, Zahra Batool, Monica Z. Wu, Michelle L. Dubuke, Malgorzata Dobosz-Bartoszek, Joshua D. Jones, Yury S. Polikanov, Bijoyita Roy ...

This 'phase coding' model posits that during sequence encoding, the current item is represented and encoded by transient higher frequency activity, while the relative position of each item in a ...

Scientists insert variable DNA sequences coding for their proteins of interest into plasmids that carry a phage coat protein gene, an antibiotic resistance gene, and a packaging signal. Then they ...