Senate Republicans took a major step to advance President Donald Trump’s sweeping agenda early Friday morning, voting to adopt a budget blueprint that sets up a clash with House Republicans, who have put forward a competing plan.

The Senate will proceed with its own plan, Majority Leader John Thune said, continuing to cast doubt on the House's ability to pass Trump's agenda in one big bill.

The move came even though the president has endorsed the House GOP's one-bill approach while Senate Republicans want to separate his priorities into two bills.

Republicans pressed forward despite President Donald Trump's endorsement of a competing House proposal and questions about the path ahead.

President Donald Trump’s endorsement of the House budget resolution as his preferred path to pass an extension of his 2017 tax cuts, border security funding and other parts of his agenda would likely require deep cuts to Medicaid,