Of three enzymes encoded by HIV–reverse transcriptase, protease, and integrase—only the first two have been exploited clinically as inhibitor targets. Efforts to develop inhibitors of purified ...

A new vector system known as lentiviral vectors can permanently integrate the gene into dividing and non-dividing cells. The capacity of lentiviral vectors to reliably integrate at various genomic ...

Vectors, both viral and non-viral, continue to further progress gene therapy for a variety of disease states. With further innovation, the approaches can expand their reach even further. Gene therapy ...