In a new study, researchers systematically mapped the surface proteins on human leukocytes to examine interactions between their cell-surface proteomes and develop a physical wiring diagram ...

By using advanced screening methods to tune into the communications taking place between individual cells, scientists have produced the first full connectivity map of the human immune system. This ...

Shilts is first author of the researchers’ published paper in Nature, which is titled “ A physical wiring diagram for the human immune system,” in which they concluded, “To our knowledge ...

Researchers have created the first full connectivity map of the human immune system, showing how immune cells communicate with each other and ways to modulate these pathways in disease.

Figure 3: Mechanical forces in immune cell–cell interactions. a | A diagram showing the lymphocyte immunological synapse.

The study is “unique in demonstrating that people’s immune system can be primed just by the visual recognition that someone looks sick,” Irwin adds to Simon Makin at Science News.

Diagram showing the mechanism discovered in the study. Inflammation of the intestines in ulcerative colitis results from an ...