You can disable Windows Thumbs.db files from being created using Group Policy or Registry Editor. Stop or prevent Windows from creating Thumbs.db!

If you can delete it, good, else you may need to first disable thumbs.db creation and then try. Read: The action can’t be completed because the file is open in another program.

Windows loves to create thumbs.db files, but they can cause problems, especially on a network. Here's what you can do about them.