Mouse jitters in League of Legends can be caused by dust on the mouse sensor or mouse pad, as well as faulty wireless transmitter/receiver and USB Port.

Dirt could be covering the infrared sensor under your mouse. There could also be dirt inside the scroll wheel, in which case you’ll have to open the mouse with a screwdriver and use canned air ...

This week’s edition of Data Doctors dives into issues with your computer mouse, and how it can be fixed, whether it’s a hardware, software or malware issue.