Too many USB issue notifications? Learn how you can enable or disable Notification of USB issues in Windows using Registry and Settings options.

One of the simplest methods to disable USB ports in Windows 10 is through the Device Manager. Here’s how you can do it: Modify the Start Value: Double-click on the "Start" value and change the ...

The USB port control native to Windows XP and Windows Server 2003 is extremely limited. You can disable ports or render them read-only, but finer control over allowed devices or file types is lacking.

So disallow HID_DEVICE, HID_DEVICE_SYSTEM_MOUSE and HID_DEVICE_SYSTEM_KEYBOARD. This would, if I'm following Coleman's link right, disable all USB input devices.