This Collection supports and amplifies research related to SDG 3 and SDG 9. Mitochondrial dysfunction has been identified as a hallmark of aging, playing a central role in age-associated decline ...

Researchers from Inserm and the University of Bordeaux, in collaboration with the University of Moncton, have developed an ...

Scientists at Scripps Research published findings that demonstrate how a mitochondrial protein structure is necessary to activate the cell’s integrated stress response (ISR), which is a critical ...

Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its ...

Like bees breathing life into gardens, providing pollen and making flowers blossom, little cellular machines called mitochondria breathe life into our bodies, buzzing with energy as they produce the ...

Our cells produce a variety of proteins, each with a specific role that, in many cases, means that they need to be in a particular part of the cell where that role is needed. One of the ways that ...

The brain requires continuously high energy production to maintain ion gradients and normal function. Mitochondria critically undergird brain energetics, and mitochondrial abnormalities feature ...

This Collection brings mitochondria into focus within the aging field, emphasizing their central role in cellular senescence, local and systemic dysfunction, and age-related disease.