In the mid-1800s, Lionel Smith Beale, an English physician and microscopist at King’s College in London, peered through his microscope at a smear of saliva and mucus coughed up by a man with cancer of ...

Using computer simulations, chemists have discovered how nuclear bodies called nucleoli interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets ...

Nocturnal and diurnal mammals see the same -- but only for a brief time. When mice are born, the chromatin in the cells of their eyes has a diurnal structure. Day by day, the layout of this chromatin ...

A team of scientists has uncovered the physical principles - a series of forces and hydrodynamic flows - that help ensure the proper functioning of life's blueprint. Its discovery provides new ...

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease. Fused in sarcoma (FUS) is a DNA/RNA binding protein and mutations in FUS cause a subset of familial ALS. Most ALS ...

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated ...

The Dere lab specializes in kidney cancer and VHL (von Hippel Lindau) disease focused on understand fundamental aspects of how non-chromatin functions of chromatin modifiers contribute to oncogenesis.

This is a preview. Log in through your library . Abstract It is proposed that elongation of the nucleus in spermatids of Marchantia results from interaction between its membranous envelope and ...

As ever-improving analytical techniques enable scientists to better understand gene-expression changes in Alzheimer’s disease, Vivek Swarup, University of California, Irvine, and colleagues realized ...

Fred Hutchinson Cancer Center DNA-packaging expert Toshio Tsukiyama, PhD, DVM, was elected to the American Academy of Microbiology class of 2024. Members undergo a peer-reviewed election process to ...