Conformational change of a biomolecule—a change in its structure—is the ultimate basis for signaling in biology. A convenient and direct way of detecting structural changes in protein targets ...

In general, 2-date forest change detection algorithms are more flexible than time-series methods and use richer spectral information. The 2-date method can easily determine changes between image ...

We propose a self-normalization sequential change-point detection method for time series. To test for parameter changes, most traditional sequential monitoring tests use a cumulative sum-based test ...