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Array-based comparative genomic hybridization (CGH) is a technique that allows genome wide screening of gains and losses in DNA copy number.
In our laboratory, we have used HR-CGH as a screening method for cryptic chromosomal imbalances for several years. In an initial study, we found a cryptic chromosomal imbalance in 5 out of 50 patients ...
Detection of CNAs in AML As with MDS, early studies in AML with array CGH and SNP array showed the feasibility of interrogating AML genomes with array platforms and demonstrated their utility in ...
BioDiscovery, Inc. has announced the release of NEXUS CGH version 2, the first commercial software tool that can provide easy and powerful platform independent and cross-platform analysis of multiple ...
Comparative genomic hybridization (CHG) provides the densest coverage of probes for CNV detection, but the traditional technique using bacterial artificial chromosome arrays is time consuming and not ...
As an example of application, this new statistic is used to analyze array-based comparative genomic hybridization (array-CGH) data. Array-CGH measures the number of chromosome copies at each genome ...
Roche NimbleGen, Inc. has launched NimbleGen Comparative Genomic Hybridization (CGH) microarrays in a 12x135K format for analysis of DNA copy number variation. NimbleGen CGH 12x135K arrays will allow ...
Array-based comparative genomic hybridization is able to unveil previously undetectable nuances.
They recommended that advanced genomic technologies, such as array CGH, be broadly deployed by cell culture banks to ensure consistency of the cells they provide to the research community.
Due to its higher resolution, oligo array CGH has recently made strong inroads in the cytogenetic lab. It’s not surprising. With an increased sensitivity of more than 1,000-fold, microarrays can ...
The use of array-based technologies (array CGH and SNP arrays) can identify deletions and amplifications in a subset of MDS and AML patients that probably contain genes that contribute to ...
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