If certain vaccines aren't recommended by the ACIP, it may lead to parents or guardians facing out-of-pocket costs if their children receive the shot. It could also mean the shots aren't covered by the Vaccines for Children (VFC) program, a federally funded program that provides no-cost vaccines to eligible children.

The AAP's new immunization guidelines prioritize COVID-19 vaccinations for young children, diverging from CDC recommendations while aligning on other vaccines.