Although the evidence is not complete, this is certainly a reasonable strategy, as is initial therapy with a ß-blocker, unless contraindicated, because the UKPDS study showed ß-blockers to be ...

When therapy was intensive, the UKPDS study reported a higher proportion of hypoglycemic episodes. Over a 6-year period, the mean proportion of all patients per year with 1 or more major ...

Treating type 2 diabetes patients as early as possible by controlling blood sugar with insulin and drugs can prolong life and reduce the risk of future complications such as heart attacks, kidney ...

Five studies fulfilled their inclusion criteria: the United Kingdom Prospective Diabetes Study (UKPDS), the Prospective Pioglitazone Clinical Trial in Macrovascular Events (PROactive), the Action ...