The brains of people with recurrent depression have a significantly smaller hippocampus - the part of the brain most associated with forming new memories - than healthy individuals, a new global study ...

A new clinical trial found that psilocybin therapy eased recurring depression symptoms within days, with some benefits ...

Depression can feel like the demands of the outside world cost you more than the resources you gain each day. You spend energy and time working, using cognitive resources to have conversations, or ...

The Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial evaluated 284 patients with CAD who had major depression for at least four weeks and Hamilton ...

Psilocybin has been proposed as a rapid-acting antidepressant (onset <2 weeks) with sustained effects (>6 weeks), but evidence from randomized clinical trials remains limited, particularly in the ...

Depression affects about 5.8% of the Brazilian population and presents a wide range of symptoms, intensities, and durations.

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

NEW YORK (Reuters Health) - Maintenance therapy with the antidepressant Lexapro (also known as escitalopram) significantly reduces the risk for recurrent depression, according to study findings. Sign ...

A single dose of the psychedelic substance psilocybin can provide rapid relief from depressive symptoms—within just a few ...