Randomized controlled trials could be harming nonprofits, experts argue

In the 1940s, medical researchers began using randomized controlled trials to assess the efficacy of health interventions. In ...
STAT

Why Silicon Valley should demand clinical trials for its medical AI

Elemento is the director of the Englander Institute for Precision Medicine at Weill Cornell Medicine. Sternberg is the clinical director of the Englander Institute for Precision Medicine. Khozin is ...
Medycyna Praktyczna

Efficacy of unilateral laparoscopic-guided abdominal wall block compared to local infiltration in postoperative analgesia following laparoscopic cholecystectomy: a single ...

Introduction: Effective postoperative analgesia is crucial for recovery after laparoscopic cholecystectomy (LC). Although local anaesthetic infiltration (LAI) is commonly used, transversus abdominis ...
Lupus Science & Medicine

Can disease activity and treatment responses be captured by a core set of domains in SLE clinical trials? An analysis of phase III belimumab trial data

Objective Outcome measures used in SLE randomised controlled trials (RCTs) have impeded trial success and drug approval. In ...
BMJ Open

Family-supported hearing aid use behaviour intervention to improve outcomes in older adults at high risk for dementia (SOUND): study protocol for a randomised co…

Background Hearing loss (HL) imposes a substantial burden on families and society and is the largest modifiable risk factor ...
Heart

Comprehensive guideline-directed medical therapy strategies on health status outcomes in patients with heart failure: the LAQUA-HF randomised clinical trial

Background Introduction of guideline-directed medical therapy (GDMT) has transformed the care of heart failure (HF) with ...
ascopubs.org

A multicenter, randomized, controlled, open-label trial to determine the optimal duration of steroid therapy for mild pneumonitis associated with immune checkpoint inhibitors.

Results of a multisite randomized trial of Bright IDEAS-Young Adults: Efficacy of problem-solving skills training on distress and health-related quality of life. This is an ASCO Meeting Abstract from ...