Proteins play a key role in the life sciences -- from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals. Scientists have developed a method that ...

This article is based on a poster originally authored by Sunidhi Shetty, Narasimha Murthy Bandaru, Anna Moberg and Marco Manni, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...

Proteins play a key role in the life sciences - from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals. Scientists at the Technical University of ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

In a study published in Nature Methods, a research group developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Double-stranded RNA (dsRNA) is a critical immunostimulatory impurity in mRNA production and poses a problem for the downstream purification methods vital to manufacturing mRNA vaccines and ...

The team has further developed the method of chromatography. For this purpose, they have developed a light-sensitive molecular appendix that serves as an anchor for the target protein. It binds the ...