Lysosomes are the control centers for the metabolism of cells and tissues, including the brain. They break down defective proteins and other macromolecules into their basic building blocks.

Extracellular vesicles (EVs) are tiny biological bubbles that carry nucleic acids and proteins between cells, playing an ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic ...

For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

Researchers have created nanoparticles that can remove disease-driving proteins while also delivering a chemotherapeutic or ...

A newly identified role for the neuronal MPS shows it controls nutrient uptake by acting as a gatekeeper. Its disruption ...

Our reliance on these molecules is incredible.

Findings from preclinical studies could point to therapeutic strategies for Huntington’s disease, as well as other neurodegenerative disorders and potentially cancer.