The alternative text for this image may have been generated using AI. Figure 2: Decoding by custom-made FIT systems that consisted of in vitro tRNA transcripts. The alternative text for this image may ...
Local slowdown of translation by nonoptimal codons promotes nascent-chain recognition by SRP in vivo
The genetic code allows most amino acids a choice of optimal and nonoptimal codons. We report that synonymous codon choice is tuned to promote interaction of nascent polypeptides with the signal ...
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