Nature

A polymorphic variant of the gene coding desmoglein 1, the target autoantigen of pemphigus foliaceus, is associated with the disease

Two polymorphic markers were identified on the desmoglein 1 gene which encodes the autoantigen targeted by pathogenic antibodies in pemphigus foliaceus (PF), a cutaneous autoimmune blistering disease.
ascopubs.org

Polymorphism of nucleotide excision repair genes as predictors for clinical outcome in advanced gastric cancer patients treated with oxaliplatin-based chemotherapy

Polymorphisms in epidermal growth factor (EGF) and proteinase activated receptor 1 (PAR-1) associated with tumor recurrence in localized adenocarcinoma (EA) of the esophagus treated with surgery alone ...
ascopubs.org

Frequency of UGT1A1*28 gene polymorphism in Chinese gastrointestinal cancer patients and its relationship with irinotecan-related diarrhea.

New analysis of the hypertension mechanism in bevacizumab-treated patients using 3-tesla dynamic contrast-enhanced magnetic resonance imaging. Background: The incidence of irinotecan-related adverse ...
Medscape

Metabolism and Transport of Tamoxifen in Relation to Its Effectiveness

Tamoxifen reduces the rate of breast cancer recurrence by approximately a half. Tamoxifen is metabolized to more active metabolites by enzymes encoded by polymorphic genes, including cytochrome P450 ...
JSTOR Daily

Polymorphic Gene Markers in Mexican-Americans Residing in Southern California

The gene frequencies of nine different genetic polymorphic markers [ABO, MNS and blood groups; haptoglobin, transferrin, Gc protein, complement (C3), properdin factor B and α₁-antitrypsin] were ...
Nasdaq

Solid Biosciences to Initiate Phase 1b Trial for SGT-501, a Novel Gene Therapy for Catecholaminergic Polymorphic Ventricular Tachycardia

Solid Biosciences announces Phase 1b trial for SGT-501, a gene therapy for catecholaminergic polymorphic ventricular tachycardia, with FDA designations. Solid Biosciences Inc. has announced the ...