Current platelet function assays rely on light transmission aggregometry or proprietary cartridge-based systems, which require specialized expertise, dedicated instruments, and expensive consumables ...

BACKGROUND: Despite antiplatelet therapy, some patients remain at high ischemic risk because of drug nonresponsiveness or high residual platelet reactivity). We aimed to target an orphan platelet GPCR ...

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

WASHINGTON, DC—Additional evidence, this time from a phase IIb trial in healthy people ages 50 to 80, supports that bentracimab (PhaseBio) provides a near-immediate reversal of ticagrelor’s ...

Use of platelet function testing during dual antiplatelet therapy, including a P2Y12 antagonist, in acute coronary syndromes does not improve clinical outcomes. Researchers at King's College London ...

Scientists at Uppsala University have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which ...

The document follows two earlier consensus documents, released in 2013 and 2016. Dominick Angiolillo, MD, PhD (University of Florida College of Medicine – Jacksonville), senior author of the paper, ...

Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...

One of the side effects of aspirin is reduced platelet function. Aspirin can potentially make issues with blood clotting worse. Thrombocytopenia is the medical term for low platelet count. Platelets ...

PlateletDiagnostics develops novel immune-based platelet function assay to monitor antiplatelet therapy: Watertown, Massachusetts Wednesday, April 8, 2026, 18:00 Hrs [IST] Platele ...