Autoimmune neutropenia of infancy (AINI) is a rare disorder characterized by neutrophil destruction secondary to antineutrophil autoantibodies. 1 Infants with AINI are at a high risk of infection; up ...

A 29-year-old woman who was 35 weeks' pregnant presented to the emergency department (ED) with perianal pain that had been worsening over the past few days. The patient explained that she had ...

Factors involved in fistulizing perianal disease pathogenesis include a genetically determined altered immune response with increased production of cytokines, leading to upregulation of matrix ...

Despite higher utilization of immunomodulators and biologics, perianal Crohn's disease (PCD), especially the severe phenotype, is associated with poor outcomes, a large population-based study from ...

Pain in the perianal region is usually due to an infection, a tear in the delicate skin lining the anal canal or prolapsed piles. Perianal pain, therefore, always warrants medical attention. Neglected ...