Thirteen patients with liver disease and an abnormal ... Informed consent was obtained from each patient before the plasma transfusions. Initial Coagulation Studies. Type-specific fresh-frozen ...

Results: A total of 2321 paired values from 539 patients were studied; 42% of data pairs had a high aPTT value relative to the anti-Xa value. Patients with elevated baseline prothrombin time ...

Patients with acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) are at high risk of bleeding with traditional artificial liver support systems.

The patient, a young man, suffered acute liver failure after receiving the therapy, Sarepta said. Liver injury is a known complication risk of Elevidys and other gene therapies that use an adeno ...