Resources for observational comparative research have expanded enormously in recent years to include very large sources of ...

• The choice between an observational study and a randomized controlled trial (RCT) is not binary. • No algorithm exists for determining whether an observational study or an RCT is best for answering ...

The use of data from observational studies has a long tradition in epidemiological research. A series of complex study designs and analysis procedures, such as propensity score methods, have been ...

A recent study published in Health Data Science led by Zhilong Zhang from the Institute of Medical Technology at Peking University Health Science Center and Professor Luxia Zhang from the National ...

• Accounting for bias is a major challenge confronting the use of observational data to gain important insights into real-world treatment effects. • No single study design will satisfy all information ...