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DNA holds our genetic blueprints, but its cousin, RNA, conducts our daily lives I n 1957, just four years after Francis Crick ...
Finding function for noncoding RNAs using a new kind of CRISPR RNA-targeting CRISPR reveals that hundreds of noncoding RNAs are essential -- not 'junk' -- including in human development and cancer ...
As the most abundant type of long noncoding RNA in the cardiac cells, CARMN-RNA seems to play a critical role in enhancing the flexibility of blood vessels.
13d
News-Medical.Net on MSNNext-gen sequencing reveals the regulatory potential of the non-coding genome
The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a ...
“To elucidate the function of this long noncoding RNA (lncRNA), we knocked down Snhg11 in the DG of wild-type mice,” they wrote.
Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia The following represents disclosure information provided by authors of this manuscript. All ...
When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...
10d
AZoLifeSciences on MSNExploring the Regulatory Potential of "Junk DNA"
The non-coding genome, once referred to as "junk DNA," is now understood to be a fundamental regulator of gene expression and ...
3monon MSN
RNA binding proteins found essential for regulatory T cell function and immune homeostasis
Immunologists from the Institute have been the first to uncover a role for a family of RNA binding proteins in the function ...
“This survey of functional noncoding RNAs advances our understanding of the human genome and demonstrates the potential of CRISPR screens that specifically target RNA—even those that don’t ...
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