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In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...
Finding function for noncoding RNAs using a new kind of CRISPR RNA-targeting CRISPR reveals that hundreds of noncoding RNAs are essential -- not 'junk' -- including in human development and cancer ...
DNA holds our genetic blueprints, but its cousin, RNA, conducts our daily lives I n 1957, just four years after Francis Crick ...
The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a ...
“To elucidate the function of this long noncoding RNA (lncRNA), we knocked down Snhg11 in the DG of wild-type mice,” they wrote.
The non-coding genome, once referred to as "junk DNA," is now understood to be a fundamental regulator of gene expression and ...
Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia The following represents disclosure information provided by authors of this manuscript. All ...
The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding ...
When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...
“This survey of functional noncoding RNAs advances our understanding of the human genome and demonstrates the potential of CRISPR screens that specifically target RNA—even those that don’t ...