San Francisco 49ers vs Tampa Bay Buccaneers NFL game
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Get the best early 49ers vs. Buccaneers predictions ahead of Sunday's Week 6 clash. Free NFL picks for October 12.
Unfortunately for the 49ers, McCaffrey is averaging just 3.1 yards per carry this season, and that's a big reason their offense is so mediocre. They can't run the ball effectively with McCaffrey. Meanwhile, his backup, Brian Robinson Jr., is averaging a respectable 4.0 yards per carry behind the same offensive line.
Los Angeles Rams wide receiver Puka Nacua has broken yet another NFL record after he recorded his eighth catch of the evening in the Week 5 game against the San Francisco 49ers.
Our 49ers vs. Rams predictions believe Matthew Stafford and the potent Los Angeles pass attack will pull away from San Francisco on Thursday, October 2, 2025. Free NFL picks for Week 5.