Nature

Inositol Trisphosphate Receptor Signaling and Calcium Dynamics

Inositol trisphosphate receptors (IP3Rs) are pivotal Ca²⁺ channels embedded in the membrane of the endoplasmic reticulum. Their activation by inositol 1,4,5-trisphosphate (IP3) and Ca²⁺ gives rise to ...
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Agonist concentration–dependent changes in FPR1 conformation lead to biased signaling for selective activation of phagocyte functions

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 31 (August 2, 2022), pp. 1-8 (8 pages) The bacteria-derived formyl peptide fMet-Leu-Phe (fMLF) is a ...
ascopubs.org

Expression of the type 3 inositol 1, 4, 5-trisphosphate receptor according to the chronic liver disease etiology in hepatocellular carcinoma.

Lenvatinib plus hepatic arterial infusion of modified FOLFOX regime in patients with advanced hepatocellular carcinoma. This is an ASCO Meeting Abstract from the 2020 ASCO Annual Meeting I. This ...