Leg cramps—often referred to as a charley horse—are painful, involuntary contractions of the muscles in your thigh or calf. They commonly occur from dehydration or muscle overexertion.

Leg cramps at night are a problem that wakes you up in the middle of your sleep. The pain is so intense that it becomes difficult to even move your legs. According to American Family Physician ...

If you have nocturnal (nighttime) leg cramps, your doctor might prescribe quinine (Qualaquin)-even though the U.S. Food and Drug Administration has approved it for only one purpose: to treat ...