Germinal center (GC) B cells are responsible for producing antibodies. The cells have some of the highest proliferation rates of all mammalian cells, yet their metabolism is unusual and ...

The research team plans to investigate further the biological mechanisms behind the faster immune response from ...

B cells in lymphoid organs undergo germinal center reactions. The image on the left is an immunized mouse spleen with activated B cells (brown) that produce antibodies. At right, top: a scanning ...

Patients with a immunohistochemically defined, germinal-center tumor subtype have an ... paraffin-embedded biopsies using antibodies against CD10, BCL-6 and MUM-1 allows DLBCL subtypes to be ...

Previous work had suggested pausing Bruton tyrosine kinase (BTK) inhibitors before COVID-19 vaccination might boost immunity ...

Activated B cells give rise germinal centers (shown in red), where mature B cells proliferate and produce highly specific antibodies against pathogens. Top left: normal germinal center in a mouse ...