Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

A new tool greatly improves scientists' ability to identify and study proteins that regulate gene activity in cells, ...

For the first time, scientists can view RNA molecules directly inside cells and tissue in minute detail and across the entire ...

Previously unmapped sections of the genome explain how cells sense their mechanical environment and could open new paths for ...

Gene expression snapshots paint an incomplete picture of development. By tracking cell shape changes in live tissues, scientists may fill in the missing pieces.

A team of researchers at Karolinska Institutet, together with colleagues from Linköping University, has uncovered the ...

Single-cell analyses revealed molecular profiles that can distinguish PTSD from depression, potentially leading to better drugs for this psychiatric disorder. To test this hypothesis, Girgenti and his ...

The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, ...