Organisms are made up of cells, and in each of those cells, a genome encodes the instructions for that organism to grow and survive. The human genome has at least 20,000 genes, and the expression of ...

Researchers have unveiled CREsted, a comprehensive software powerhouse. CREsted doesn’t just describe how DNA works; it allows scientists to design entirely new, synthetic enhancers—short DNA ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

A multi-institutional team of researchers led by Case Western Reserve University has identified a pattern of clustered genetic changes that appear to encourage growth of colorectal cancer tumors—a ...

This color-coded graphic shows different populations of cells in the mouse brain, each one targeted by one of the genetic tools developed by scientists at the Allen Institute and other institutions.

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

Scientists say they’ve put together a new kind of molecular toolkit that could eventually be used to treat a variety of brain diseases, possibly including epilepsy, sleep disorders and Huntington’s ...