The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...

Metabolism and individuality in drug response The need to understand individuality in drug response and associated benefits is a primary force behind the current industry trend toward the ...

Even well-known drugs can cause entirely unpredictable effects on metabolism, Swiss researchers have shown. Rapidly mapping ...

The NMR and Drug Metabolism Core at Baylor College of Medicine offers tools to support the discovery, synthesis, screening, optimization, metabolism and pharmacokinetics of small molecule ligands or ...

Individuals respond to drugs in different ways, and it appears that each person’s microbiome may play a significant role in how drugs are absorbed and metabolized by the body. I have followed ...

Researchers at the University of Basel are able to test in parallel the effects of over 1,500 active substances on cell ...

A high-resolution spatial map of the human hypothalamus makes it possible to identify specific cells, determine their exact ...

Researchers are able to test in parallel the effects of over 1500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown mechanisms for known medications.

Scientists have unveiled a groundbreaking method to test how thousands of active substances influence cellular metabolism ...