Diffuse coronary artery disease is a subtype of coronary artery disease (CAD) in which larger sections of coronary arteries have a high plaque buildup. It is less common than focal CAD and can be more ...

Diffuse midline glioma (DMG) is a rare form of brain tumor that mostly occurs in children and young adults. It can be highly aggressive and difficult to treat. DMGs form within the central nervous ...

Diffuse axonal injury (DAI) is a form of traumatic brain injury. It happens when the brain rapidly shifts inside the skull as an injury is occurring. The long connecting fibers in the brain called ...

Primary Tumor Resection Before Systemic Therapy in Patients With Colon Cancer and Unresectable Metastases: Combined Results of the SYNCHRONOUS and CCRe-IV Trials Histone 3 (H3) K27M–mutant diffuse ...

Hereditary cancer syndromes are disorders that increase your risk of certain cancers due to mutations in one or more genes inherited from your parents. Genetic testing can help you determine your risk ...

Modeyso is the first FDA-approved treatment for recurrent H3 K27M-mutant diffuse midline glioma, offering a new option for patients with limited choices. Phase II trials showed a 22% objective ...

Abbreviations: AKT, protein kinase B; BAD, BCL2-associated death promoter; BAK, BCL2 antagonist killer; BAX, BCL2-associated X protein; BCL, B-cell lymphoma; BTK ...