Diabetes. 2013;62(12):3976-3986. The power calculations required 700 subjects (350 in each treatment arm) for each of the primary prevention and secondary intervention cohorts in order to detect a ...
"The landmark 10-year, 1,440-person Diabetes Control and Complications Trial (DCCT), published in 1993, established hemoglobin A1c as the gold standard for evaluating the risk for complications ...