A new AI tool reveals how tangled DNA knots impact health and disease, offering insights for drug discovery and genetic ...

By creating a more true-to-life representation of DNA's environment, researchers have discovered that strand separation may take more mechanical force than the field previously believed.

Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation—the essential process a "resting" double helix ...

DNA doesn’t knot under stress. A new study finds it coils into plectonemes, reshaping models of genome mechanics. For decades ...

Lead author of "Distinct regulation of ATM signaling by DNA single-strand breaks and APE1," Haichao Zhao offered that the research may support future clinical trials – both for attacking cancer ...