In contrast to conventional organic synthesis, mechanochemistry does not use solvents that eventually become industrial wastes. Thus, mechanochemistry is environmentally friendly and enables us to ...

Despite recent proliferation of programmable robotic chemistry hardware, current chemical programming ontologies lack essential structured programming constructs like variables, functions, and loops.

The alternative text for this image may have been generated using AI. We predicted that the strategy of common lost chemical pieces should apply broadly to chemical synthesis, as fragmentation is a ...

Highly reactive organometallic reagents, like organolithiums (molecules with a carbon–lithium bond) are essential reagents in organic synthesis because of their applications from polymer synthesis to ...

Plants are undeniably one of nature's most promising sources of new medicines, with monoterpenoid indole alkaloids (MIAs) ...

Researchers have simplified the operation of an important class of chemical transformation: synthesis of beta-lactams, the intricate scaffold of many antibiotics. Their experimental protocol minimizes ...

The dataset, which the researchers have made available on the Open Reaction Database, is nearly five times as large as the ...

With artificial intelligence, scientists can design increasingly complex small molecule structures. Automation is critical for transforming these compounds from designs on a screen into actual ...

Osaka, Japan – While we appear to live in a world of plenty, behind the scenes, sourcing sufficient amounts of key ingredients can be challenging. For example, the synthesis of certain antibiotics, ...