City St. George’s researchers identified 9 genetic signatures and epigenetic changes driving lapatinib resistance in HER2-positive breast cancer. Cancer scientists from City St George’s, University of ...

Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown—yet understanding this is crucial for optimizing ...

Study suggests that persistently activated ATF6α is a tumor driver, a potential stratification marker for immunotherapy response, and a therapeutic target for HCC.

This could change how we think about treating cancer. Researchers at KAIST led by Kwang-Hyun Cho have developed a method that ...

Researchers at City St. George’s, University of London, have identified a new molecular signature that may explain why ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

The following filter criteria for genes differentially expressed were used: PDAC versus normal pancreas (bulk tissue), PDAC versus normal pancreas (microdissected normal ductal cells), and PDAC versus ...

What if a cup of coffee could help treat cancer? Researchers at the Texas A&M Health Institute of Biosciences and Technology ...

New research shows a common skin fungus can help melanoma spread by changing cancer cell movement and energy use.

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons ...