Antibody-drug conjugates are rapidly expanding cancer therapies, with 19 approved globally and many more in development, but ...

Region-specific biomarkers FGFR4, FLT1, and WNT5A are linked to tumor behavior and therapeutic response in CRC. Comprehensive genomic profiling (CGP) aids in precision medicine by identifying genetic ...

A Northwestern team transformed a common chemotherapy drug into a powerful, targeted cancer therapy using spherical nucleic acids. The redesign dramatically boosted drug absorption and cancer-killing ...

KRAS was long thought undruggable in cancer until scientists discovered a hidden binding pocket in mutant KRAS, leading to targeted therapies. In this discussion, Asfar S. Azmi, associate professor of ...

Researchers at the University of British Columbia and BC Cancer have developed a new way to target proteins long considered "undruggable," opening the door to new treatments for prostate cancer and ...